­
­
­
­

Inventi Impact: Dermatology

Articles

  • Inventi:hdr/13967/14
    Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skinlightening:\nA Pilot Clinical Trial with 30 Volunteers
    01-Jan-1970 Research 2014 : October - December
    Kao-Sung Tsai, Tzu-Chun Lin, Meng-Tse Wu, Jui-Lung Shen, Ming-Ya Mao, Huey-Yi Chen, Yung-Hsiang Chen, Wen-Chi Chen

    Topical traditional Chinese medicine- (TTCM-) related contact dermatitis is not uncommon but ignored. Patch and photopatch\ntests using 6 individual herbal ingredients and Bai-Zhi-Kao (BZK;???), a skin-lightening TTCMpreparation, were conducted\non 30 participants. Twenty-five subjects showed at least 1 positive reaction, including 6 (20.0%) participantswho reacted to BZK.The\nmajority reacted to Radix Ampelopsis japonica (Bai-Lian;??) (60.0%), whereas few reacted to Rhizoma Bletilla striata (Bai-Ji;?\n?) (16.7%), Rhizoma Atractylodis macrocephalae (Bai-Zhu;??) (10.0%), Radix Angelicae dahuricae (Bai-Zhi;??) (3.3%), and\nHerba asari (Xi-Xin;??) (3.3%). In the photopatch test, 3 participants (10.0%) reacted positively to BZK and 10 to ?1 constituent;\nhowever, all reacted to Radix Angelicae dahuricae (26.7%), Radix Ampelopsis japonica (13.3%), and Rhizoma Bletilla striata (3.3%).\nIn contrast, no subjects showed positive reactions to SclerotiumPoria cocos (Bai-Fu-Ling;???).Thus, BZK and its constituents\nmight present potential latent risk of contact dermatitis owing to the possible presence of Radix Ampelopsis japonica and Radix\nAngelicae dahuricae. Furthermore, TTCMs, particularly cosmetic products,must be used carefully, with ample warning of potential\ncontact dermatitis risk.

    How to Cite this Article
    CC Compliant Citation: Julien Lambert, â??Kao-Sung Tsai, Tzu-Chun Lin, Meng-Tse Wu, et al., â??Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skin-Lightening: A Pilot Clinical Trial with 30 Volunteers,â? Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 609064, 8 pages, 2014. doi:10.1155/2014/609064. Copyright © 2014 Kao-Sung Tsai et al. This is an open access article distributed under the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Download Full Text